SRHC Type III Powder (DBBM-SRHC001)
Product Features
SRHC Type III Powder is a synthetic recombinant human collagen. Type III collagen is a structural protein that makes up the extracellular matrix (ECM) and provides space for cell growth with a supportive function. Type III collagen plays an important role in skin elasticity and moisturizing, and it also works significantly for scar healing and anti-aging. SRHC Type III was selected using highly bioactive fragments from the amino acid sequence of natural human Type III collagen, and genetic engineering techniques were used with eukaryotic yeast to construct an expression system by using biological fermentation technology.
- 100% homologous with human collagen, highly biocompatibility
- Multi-stage purification
- Lyophilization preparation
- Higher purity
- Safer expression in eukaryotic yeast
- Extra-long sequences
- Higher activity
INCI Name: sh-Polypeptide-123, Mannose, Glucose
Functions: Protective Agent
Ingredient Origin: Fermentation
Labeling Claims: Allergen-free, Halal, Non-Toxic, Odor-free, Vegan, Animal Products-free, Not Listed In California Proposition 65, Biocompatible
Benefit Claims: Collagen Boosting, Moisturizing, Regenerating, UV Protection, Healing, Skin Barrier, Anti-Aging, Redness Reduction, Free Of Off-Odors, Firming, Anti-Wrinkle, Nourishing, Restoring, Improves Skin Elasticity, Reduces Skin Damage, Soothing
Certifications & Compliance: ISO 14004, Vegan, Halal
Synonyms: Anhydro-mannose, D (+)-Mannose, NSC 26247
Request Document
Safety Data Sheet, Technical Data Sheet, Brochure are available under request.
Applications & Uses
Applications: Personal Care, Beauty & Care
Application Format: Creams, Leave On, Lotions, Masks, Rinse Off, Serum
Skin Care Applications: Body Cream, Body Lotion, Facial Sheet Mask, Skin Cleanser, Skin Serums
Sun Care Applications: Sunscreen Cream, Sunscreen Lotion
Treatment Product Applications: Scar Treatment
Use Level: 0.01 - 5%
Properties
Physical Form: Powder
Appearance: White to off white solid
Odor: No or slightly characteristic smell
Microbiological Values
| Value | Units | Test Method / Conditions | |
|---|---|---|---|
| Total Number of Colonies | max. 1000 | CFU/g | - |
| Total Number of Molds and Yeasts | max. 100 | CFU/g | - |
| Staphylococcus Aureus | None | - | - |
| Pseudomonas Aeruginosa | None | - | - |
| Heat Resistant Coliform | None | - | - |
Specifications
| Value | Units | Test Method / Conditions | |
|---|---|---|---|
| Collagen Content | 80 - 100 | % | - |
| pH | 3.5 - 7.0 | - | - |
| Loss on Drying | max. 15.0 | % | - |
| Residue on Ignition | max. 2.0 | % | - |
| Lead Content | max. 10 | mg/Kg | - |
| Mercury Content | max. 1 | mg/Kg | - |
| Arsenic Content | max. 2 | mg/Kg | - |
| Cadmium Content | max. 5.0 | mg/Kg | - |
| Methanol Content | max. 2000 | mg/Kg | - |
| Molecular Weight | 43.6 | kDa | - |
Technical Details & Test Data
Clinical Trials
Volunteers applied 0.2% SRHC Type ll cream to the entire face every morning and evening for 28 days.
In Vitro Efficacy
1. Restoration Capacity Assessment, Cell scratch test (HACAT)
Result: SRHC Type ll significantly promoted cell migration and had tissue damage repair function.
2. Anti-Wrinkle Effect - In vitro ex vivo skin model Masson staining experiments
Result: SRHC Type llI had a significant elevating effect on collagen fiber content for UV-induced UV damage with 0.2% SRHC Type lII.
3. Soothing Inflammation
a. EpiKutis epidermal model Detection of PGE2
Result: 0.2% SRHC Type III had a significant inhibitory effect on PGE2 induced by SLS stimulation and reduced PGE2 secretion level.
b. EpiKutis epidermal model TRPV1 test
Result: 0.2% SRHC Type III significantly down-regulated TRPV1 protein expression induced by SLS stimulation
Packaging & Availability
Packaging Type: Bags
Packaging Information: Packaging: 1kg/bag, 5kg/bag or according to the order requirements.
Inner: PE bag; Outer: aluminum bag
Shelf Life: 2 Years
Storage Information: Keep container closed at room temperature.